Get Better Skin with Plinest Treatment

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Plinest® treatment is an injectable skin booster made from polynucleotide (PN), which are DNA molecules extracted from Italian trout using patented Highly Purified Technology (HPT) patented by Mastelli Aesthetic, Italy. Plinest addresses various skin concerns, including wrinkles, fine lines, loss of volume, and hydration issues, for a comprehensive skincare solution by using non-surgical approach to rejuvenating the skin, providing natural-looking results with minimal downtime.

What is Plinest Treatment and how it works?

Plinest is clinically proven to improve overall skin healthy by promoting bio-revitalisation to reverse signs of aging, promote collagen formation to repair damaged skin, restore skin hydration and elasticity to give you a smooth, radiant and healthy skin.

How Plinest Treatment can help you?

A. Reduce Appearance of Scar and Stretch Marks

When injected intradermally, PN-HPT® promotes a trophic and stimulating action on existing fibroblasts and has been found to increase collagen synthesis, as well as the viability and number of fibroblasts.

B. Skin Radiance

Research also indicates that PLINEST® can improve skin’s hydration and scavenging ability, leading to overall skin enhancement. Patients are advised to have three to four PLINEST® treatments spaced two to three weeks apart for best results.

C. Clear the Skin and Healthier Looking Skin

By regenerating fibroblasts, Plinest is able to improve the appearance of fine lines and wrinkles, hyperpigmentation and skin laxity, acne scarring and rosacea. Research has found that PLINEST® acts as ‘background preparation for the tissues’, allowing treatments that follow to have faster and stronger responses.

D. Other Beneficials

The expert consensus report into its use says that administering PLINEST® before hyaluronic acid dermal fillers ‘develops a synergic effect by associating the strong effect on turgescence improvement due to hyaluronic acid with the useful action on hydration and, even more distinctively, the powerful dermal stimulating effect exerted by PN‐HPT.

When it comes to energy devices, chemical peeling and microneedling, the experts advise that PLINEST® produces greater results if started before the second treatment – even if only performed a week before. PLINEST® has also been proven to enhance results and keep skin looking good for longer when used after other treatments.


Real-Life Results

Above is the treatment for Hormonal Acne, after 1 session of Plinest treatment
Above is the treatment for Rosacea Skin, after 2 sessions of Plinest treatment.


People who are experiencing premature skin aging with several skin conditions such as skin sensitivity, enlarged pores, oily skin, wrinkles, and acne. PN treatment would be suitable for those who wish to address several skin issues at the same time. In addition, people who have acne scars also achieve good wound healing results with PN treatment.

For first-timers, we recommend that you undergo a programme of 4 sessions, with each session around 4 weeks apart. After that, you can opt for a session every 3-6 months to maintain the results of the treatment.

The whole process will take about 30 minutes. Doctor will use either cannula or direct injection to administer the product (highly purified PN) into the skin, there is only minimal discomfort during the treatment.

You may experience some skin redness and mild swelling and possibly bruising too. The downtime normally lasted for 3-5 days depending on individual. We advice to stop taking supplements or blood thinner 3 days prior to treatment.

Collagen and fibroblast stimulation and proliferation normally takes time. The result will not show immediately post treatment. Generally, it takes about 1-2 weeks after the first treatment and better results can be seen after several sessions.


Plinest treatment can be a friendly option for those seeking a subtle yet effective treatment in overall skin rejuvenation. It provides a cost-effective option for achieving a more youthful and radiant complexion without the downtime and expense associated with surgical procedures.

If you are interested in Plinest and wish to know more about it, feel free to book a consultation with Kaiteki for a personalised assessment by doctor, our doctors will evaluate your skin and give you a personalised treatment plan tailored to your needs.

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