“If you are excited to understand more about the Rejuran i vs Rejuran S, please consult our experienced doctors at Kaiteki Clinic. We will create a personalized treatment plan tailored to your needs! “
Table of Contents
Introduction
When it comes to aesthetics, one-size-fits-all is a tired myth best left behind. Today’s beauty seekers are savvier, asking the right questions and expecting tailored solutions—and rightly so.
Introducing Rejuran I and Rejuran S, two treatments that may come from the same lineage but couldn’t be more different in purpose, texture, and technique.
Knowing which one belongs in your skincare script is the difference between “good enough” and just right.
What Exactly Is Rejuran?
Before we put them head-to-head, let’s rewind a little. Rejuran is a skin-healing injectable treatment made with polynucleotides (PN) derived from salmon DNA. Why salmon? Its DNA shares a remarkably similar structure with humans, making it well-tolerated and highly effective in restoring skin health.
Rejuran works by stimulating collagen production, reducing inflammation, and strengthening the skin barrier. The result? Smoother, more youthful skin from the inside out.
But not all Rejuran formulas are created equal.
Rejuran I: The Under-Eye Solution
Think of Rejuran I as the precision artist of the Rejuran family. It’s crafted specifically for the fragile under-eye zone, where the skin is thinner, more prone to creasing, and notoriously tricky to treat.
- Low viscosity means it’s feather-light—ideal for fine lines and dehydration around the eyes.
- It helps reduce dark circles, crow’s feet, and under-eye hollows without causing puffiness.
- Because it spreads smoothly, there’s minimal risk of lumpiness—a common complaint with generic fillers.
Patients who want a fresher, more awake look without the heaviness of traditional fillers often turn to Rejuran I for that touch of refinement.
Rejuran S: The Scar Solution
On the flip side, Rejuran S comes in like a sculptor—designed to reshape and refine where the skin’s texture has lost its smoothness due to trauma, usually in the form of acne scars.
- This version has a higher viscosity and is injected more deeply.
- It works by remodelling fibrotic scar tissue and stimulating collagen from within.
- Rejuran S is especially effective on atrophic acne scars—those sunken, uneven patches that just won’t budge with surface-level treatments.
For anyone waging a long-term war against stubborn acne scars, Rejuran S is a quiet powerhouse with results that build session by session.
Key Differences
| Feature | Rejuran I | Rejuran S |
|---|---|---|
| Target Area | Under-eyes, fine lines | Acne scars, textured skin |
| Viscosity | Low – light and fluid | High – thick and concentrated |
| Injection Depth | Superficial dermis | Deep dermis |
| Primary Benefit | Hydration, brightening, wrinkle-softening | Scar remodelling, collagen stimulation |
| Risk of Puffiness | Minimal | Moderate (not used under eyes) |
| Ideal For | Tired eyes, early signs of aging | Post-acne scarring, uneven texture |
Which One Should You Choose?
The short answer: it depends on your skin’s story.
If you’re waking up to tired, shadowy under-eyes or creeping crow’s feet, Rejuran I is your ticket to looking quietly refreshed. But if the mirror reflects the aftermath of old breakouts—textural acne scars that mkakeup just can’t hide—Rejuran S delivers a slow but steady comeback.
Still unsure? Your best move is a chat with a trained aesthetic doctor who can assess your skin’s texture, thickness, and responsiveness to treatment. At Kaiteki Clinic, we approach each face as a canvas—unique, deserving of a bespoke plan, and never treated with cookie-cutter fixes.



